Multi-modality imaging in transthyretin amyloid cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Speckle Tracking and Transthyretin Amyloid Cardiomyopathy
BACKGROUND Amyloidosis is a disease caused by deposits of insoluble fibrils in extracellular spaces. The most common type of familial amyloidosis is mediated by mutation of transthyretin, especially Val30Met. Symptoms and ejection fraction decrease may occur in cardiac amyloidosis only in case of poor prognosis. Myocardial strain detected by two-dimensional speckle tracking echocardiography can...
متن کاملTafamidis in transthyretin amyloid cardiomyopathy: effects on transthyretin stabilization and clinical outcomes.
BACKGROUND Transthyretin (TTR) amyloidosis is a progressive systemic disorder caused by misfolded TTR monomers that cumulatively deposit in the heart and systemically as amyloid. METHODS AND RESULTS This phase 2 open-label trial evaluated the stabilization of TTR tetramers using 20 mg of tafamidis daily at week 6 (primary end point), month 6, and month 12, as well as safety of tafamidis treat...
متن کاملAmyloid Cardiomyopathy in Hereditary Transthyretin V30M Amyloidosis - Impact of Sex and Amyloid Fibril Composition.
PURPOSE Transthyretin V30M (ATTR V30M) amyloidosis is a phenotypically diverse disease with symptoms ranging from predominant neuropathy to exclusive cardiac manifestations. The aims of this study were to determine the dispersion of the two types of fibrils found in Swedish ATTR V30M patients -Type A consisting of a mixture of truncated and full length ATTR fibrils and type B fibrils consisting...
متن کاملMulti-modality imaging of pheochromocytoma
Pheochromocytoma, a rare neuroendocrine adrenal tumor, is often diagnosed by a combination of clinical, laboratory, and radiographic features. While the imaging features of this entity are variable, the use of complementary modalities often helps to target the diagnosis and assess the extent of the disease. We present a multi-modality evaluation of a pheochromocytoma, with CT, MR, MIBG, and pat...
متن کاملMulti-modality compressed breast imaging
ABSTRACT Measurement of breast tissue response to external stimulation has the potential to unveil additional dynamic biomarkers of disease states. Recently tumor contrast generated by breathing-gas induced vascular changes has been demonstrated using both BOLD imaging [1] and MRIguided near infrared diffuse optical tomography [2]. At the same time, in the biomedical optics community, temporall...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Cardiology
سال: 2019
ISSN: 1949-8462
DOI: 10.4330/wjc.v11.i11.266